What to give up for Peyton Manning?

Good Luck. It's hard to ess what to offer without being able to see both rosters. You need to look at his needs and adjust accordingly. That said, you're giving up a lot for Manning. Personally, I might consider this if I was really desperate for a top WR, but I certainly wouldn't throw in Jennings. Given the way Manning has been performing - he'll command a high price.